Reactome | NICD1 traffics to nucleus

Schema > Reaction > Entries

NICD1 traffics to nucleus Show undefined attributes

authored	[InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008-05-23
category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:157946] Jassal, B, 2005-01-10 12:51:46
dbId	157926
diseaseReaction	[Reaction:R-HSA-2769015] NICD1 PEST domain mutants translocate from cytosol to nucleus - Homo sapiens
displayName	NICD1 traffics to nucleus
edited	[InstanceEdit:349681] D'Eustachio, P, 2008-05-12 21:43:33
eventOf	[Pathway:R-HSA-2122948] Activated NOTCH1 Transmits Signal to the Nucleus - Homo sapiens
followingEvent	[Reaction:R-HSA-9762102] NICD1 binds the NFE2L2 promoter - Homo sapiens [Reaction:R-HSA-1912396] NICD1 binds HIF1A - Homo sapiens [Reaction:R-HSA-1912388] NICD1 displaces co-repressor complex from RBPJ (CSL) - Homo sapiens
inferredFrom	[Reaction:R-DME-159111] Drosophila NICD traffics to nucleus - Drosophila melanogaster
input	[EntityWithAccessionedSequence:R-HSA-157634] NICD1 [cytosol]
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:159104] Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos [LiteratureReference:159105] Nuclear access and action of notch in vivo
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NICD1 traffics to nucleus
output	[EntityWithAccessionedSequence:R-HSA-157939] NICD1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-157353] NEXT1 is cleaved to produce NICD1 - Homo sapiens
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:349683] Jensen, J, 2008-05-12 21:46:53
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-157926
summation	[Summation:178974] Cytosolic NICD1 translocates to the nucleus.
updateTrackers	[UpdateTracker:9788814] Update Tracker - [Reaction:157926] NICD1 traffics to nucleus - v40:[addLiteratureReference, modifyText] [UpdateTracker:9789404] Update Tracker - [Reaction:157926] NICD1 traffics to nucleus - v38:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9788814] Update Tracker - [Reaction:157926] NICD1 traffics to nucleus - v40:[addLiteratureReference, modifyText] [UpdateTracker:9789404] Update Tracker - [Reaction:157926] NICD1 traffics to nucleus - v38:[modifyText]
(normalReaction)	[Reaction:R-HSA-2769015] NICD1 PEST domain mutants translocate from cytosol to nucleus
(precedingEvent)	[Reaction:R-HSA-9762102] NICD1 binds the NFE2L2 promoter [Reaction:R-HSA-1912396] NICD1 binds HIF1A [Reaction:R-HSA-1912388] NICD1 displaces co-repressor complex from RBPJ (CSL)
(hasEvent)	[Pathway:R-HSA-2122948] Activated NOTCH1 Transmits Signal to the Nucleus
(inferredTo)	[Reaction:R-DME-159111] Drosophila NICD traffics to nucleus