Reactome | Translocation of Cyclin E:Cdk2 complex to the nucleus

Schema > Reaction > Entries

Translocation of Cyclin E:Cdk2 complex to the nucleus Show undefined attributes

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:157907] Matthews, L, 2005-01-10 10:35:10
dbId	157906
deleted	[Deleted:737632] Deletion of instance: 157904 [Deleted:737635] Deletion of instance: 157905
displayName	Translocation of Cyclin E:Cdk2 complex to the nucleus
eventOf	[Pathway:R-HSA-69202] Cyclin E associated events during G1/S transition - Homo sapiens
followingEvent	[Reaction:R-HSA-69195] Phosphorylation of Cyclin E:CDK2 complexes by WEE1 - Homo sapiens [Reaction:R-HSA-69562] Inactivation of Cyclin E:Cdk2 complexes by p27/p21 - Homo sapiens [Reaction:R-HSA-188350] CAK-mediated phosphorylation of Cyclin E:Cdk2 - Homo sapiens
input	[Complex:R-HSA-157594] CCNE:CDK2 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:187513] Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm
maxDepth	1
modified	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
name	Translocation of Cyclin E:Cdk2 complex to the nucleus
orthologousEvent	[Reaction:R-SPO-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Schizosaccharomyces pombe [Reaction:R-DDI-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Dictyostelium discoideum [Reaction:R-CEL-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Caenorhabditis elegans [Reaction:R-DME-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Drosophila melanogaster [Reaction:R-GGA-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Gallus gallus [Reaction:R-XTR-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Xenopus tropicalis [Reaction:R-DRE-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Danio rerio [Reaction:R-SSC-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Sus scrofa [Reaction:R-BTA-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Bos taurus [Reaction:R-CFA-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Canis familiaris [Reaction:R-RNO-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Rattus norvegicus [Reaction:R-MMU-157906] Translocation of Cyclin E:Cdk2 complex to the nucleus - Mus musculus
output	[Complex:R-HSA-68374] CCNE:CDK2 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-69191] Formation of Cyclin E:Cdk2 complexes - Homo sapiens
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-157906
summation	[Summation:187865] Follow their formation, the Cyclin E:Cdk2 complexes are tran...

Referrals

(replacementInstances)	[Deleted:737632] Deletion of instance: 157904 [Deleted:737635] Deletion of instance: 157905
(hasEvent)	[Pathway:R-HSA-69202] Cyclin E associated events during G1/S transition
(precedingEvent)	[Reaction:R-HSA-188350] CAK-mediated phosphorylation of Cyclin E:Cdk2 [Reaction:R-HSA-69195] Phosphorylation of Cyclin E:CDK2 complexes by WEE1 [Reaction:R-HSA-69562] Inactivation of Cyclin E:Cdk2 complexes by p27/p21