Reactome | Collagen type V degradation by MMP2,9,10

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Collagen type V degradation by MMP2,9,10 Show undefined attributes

authored	[InstanceEdit:1442471] Jupe, S, 2011-07-12
catalystActivity	[CatalystActivity:2470134] metalloendopeptidase activity of MMP2,9,10 [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:1564189] Jupe, S, 2011-09-05
dbId	1564164
displayName	Collagen type V degradation by MMP2,9,10
edited	[InstanceEdit:2580335] Jupe, S, 2012-11-12
eventOf	[Pathway:R-HSA-1442490] Collagen degradation - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-2537499] Gelatin degradation by MMP19 - Homo sapiens [BlackBoxEvent:R-HSA-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 - Homo sapiens
input	[Polymer:R-HSA-1609685] Collagen V [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2161248] MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis [LiteratureReference:1474211] Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	Collagen type V degradation by MMP2,9,10
orthologousEvent	[Reaction:R-XTR-1564164] Collagen type V degradation by MMP2,9,10 - Xenopus tropicalis [Reaction:R-SSC-1564164] Collagen type V degradation by MMP2,9,10 - Sus scrofa [Reaction:R-BTA-1564164] Collagen type V degradation by MMP2,9,10 - Bos taurus [Reaction:R-CFA-1564164] Collagen type V degradation by MMP2,9,10 - Canis familiaris [Reaction:R-RNO-1564164] Collagen type V degradation by MMP2,9,10 - Rattus norvegicus [Reaction:R-MMU-1564164] Collagen type V degradation by MMP2,9,10 - Mus musculus
output	[Polymer:R-HSA-2470128] Cleaved collagen type V fibril [extracellular region]
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2514803] Sorsa, Timo, 2012-10-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1564164
summation	[Summation:1564135] Type V collagen is a fibril-forming collagen forming a group...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-2537499] Gelatin degradation by MMP19 [BlackBoxEvent:R-HSA-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13
(hasEvent)	[Pathway:R-HSA-1442490] Collagen degradation

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