Reactome | DVL:CUL3:KLHL12:RBX1 [cytosol]

Schema > Complex > Entries

DVL:CUL3:KLHL12:RBX1 [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:1504214] ubiquitin protein ligase activity of DVL:CUL3:KLHL12:RBX1 [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-1504190] DVL is ubiquitinated by CUL3:KLHL12:RBX1 - Homo sapiens
created	[InstanceEdit:1504208] Rothfels, K, 2011-08-23
dbId	1504210
displayName	DVL:CUL3:KLHL12:RBX1 [cytosol]
hasComponent	[Complex:R-HSA-1504195] CUL3:KLHL12:RBX1 [cytosol] [CandidateSet:R-HSA-1504201] DVL [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Mus musculus [Complex:R-RNO-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Rattus norvegicus [Complex:R-BTA-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Bos taurus [Complex:R-SSC-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Sus scrofa [Complex:R-DRE-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Danio rerio [Complex:R-XTR-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Xenopus tropicalis [Complex:R-GGA-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Gallus gallus [Complex:R-DME-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Drosophila melanogaster [Complex:R-CEL-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Caenorhabditis elegans [Complex:R-DDI-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Dictyostelium discoideum [Complex:R-PFA-1504210] DVL:CUL3:KLHL12:RBX1 [cytosol] - Plasmodium falciparum
isChimeric	false
literatureReference	[LiteratureReference:1504211] The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation
maxDepth	3
name	DVL:CUL3:KLHL12:RBX1
producedByEvent	[Reaction:R-HSA-1504213] DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1504210

Referrals

(output)	[Reaction:R-HSA-1504213] DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex
(input)	[Reaction:R-HSA-1504190] DVL is ubiquitinated by CUL3:KLHL12:RBX1
(physicalEntity)	[CatalystActivity:1504214] ubiquitin protein ligase activity of DVL:CUL3:KLHL12:RBX1 [cytosol]

© 2026 Reactome

Cite Us!