Reactome | Fgd1 reactivates F420

Schema > Reaction > Entries

Fgd1 reactivates F420 Show undefined attributes

authored	[InstanceEdit:1222281] Stephan, R, 2011-01-10
catalystActivity	[CatalystActivity:1500763] oxidoreductase activity, acting on CH-OH group of donors of Fgd1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1500770] Jassal, B, 2011-08-22
crossReference	[DatabaseIdentifier:12020769] Mondo:0018076
dbId	1500781
disease	[Disease:1660556] tuberculosis
displayName	Fgd1 reactivates F420
edited	[InstanceEdit:1222482] Jassal, B, 2011-02-28
eventOf	[Pathway:R-HSA-1222541] Cell redox homeostasis - Homo sapiens
input	[SimpleEntity:R-ALL-9617032] F420(ox.) [cytoplasm] [SimpleEntity:R-ALL-30537] G6P [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:1500823] Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Fgd1 reactivates F420
output	[SimpleEntity:R-ALL-31467] D-Glucono-1,5-lactone 6-phosphate [cytosol] [SimpleEntity:R-ALL-9617033] F420(red.) [cytoplasm]
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2213261] Warner, D, 2012-04-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1500781
summation	[Summation:1500759] The enzyme in Mtb known to reduce F420 is the glucose...
updateTrackers	[UpdateTracker:9779270] Update Tracker - [Reaction:1500781] Fgd1 reactivates F420 - v66:[add_removeInput, add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9779270] Update Tracker - [Reaction:1500781] Fgd1 reactivates F420 - v66:[add_removeInput, add_removeOutput]
(hasEvent)	[Pathway:R-HSA-1222541] Cell redox homeostasis

Cite Us!