Reactome | PI is exchanged with PC by PITPNB

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PI is exchanged with PC by PITPNB Show undefined attributes

authored	[InstanceEdit:1678579] Williams, MG, 2011-10-18
catalystActivity	[CatalystActivity:9855947] phosphatidylcholine transfer activity of PI:PITPNB [Golgi membrane]
catalystActivityReference	[CatalystActivityReference:9855946] phosphatidylcholine transfer activity of PI:PITPNB [Golgi membrane] Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
dbId	1483087
displayName	PI is exchanged with PC by PITPNB
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483196] PI and PC transport between ER and Golgi membranes - Homo sapiens
followingEvent	[Reaction:R-HSA-1675883] PI is phosphorylated to PI4P by PI4KB at the Golgi membrane - Homo sapiens [Reaction:R-HSA-1675961] PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane - Homo sapiens [Reaction:R-HSA-1676185] PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane - Homo sapiens [Reaction:R-HSA-1483211] PC:PITPNB is transported from the Golgi membrane to the ER membrane - Homo sapiens
input	[SimpleEntity:R-ALL-429785] PC [Golgi membrane] [Complex:R-HSA-1524150] PI:PITPNB [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1483105] Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells [LiteratureReference:1483109] Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum [LiteratureReference:1483200] Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine [LiteratureReference:1483223] Structure of PITPbeta in complex with phosphatidylcholine: comparison of structure and lipid transfer to other PITP isoforms [LiteratureReference:1483130] Structure of apo-phosphatidylinositol transfer protein alpha provides insight into membrane association [LiteratureReference:1483188] Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol
modified	[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name	PI is exchanged with PC by PITPNB
orthologousEvent	[Reaction:R-RNO-1483087] PI is exchanged with PC by PITPNB - Rattus norvegicus [Reaction:R-SSC-1483087] PI is exchanged with PC by PITPNB - Sus scrofa [Reaction:R-PFA-1483087] PI is exchanged with PC by PITPNB - Plasmodium falciparum [Reaction:R-GGA-1483087] PI is exchanged with PC by PITPNB - Gallus gallus [Reaction:R-CEL-1483087] PI is exchanged with PC by PITPNB - Caenorhabditis elegans [Reaction:R-DME-1483087] PI is exchanged with PC by PITPNB - Drosophila melanogaster [Reaction:R-XTR-1483087] PI is exchanged with PC by PITPNB - Xenopus tropicalis [Reaction:R-BTA-1483087] PI is exchanged with PC by PITPNB - Bos taurus [Reaction:R-CFA-1483087] PI is exchanged with PC by PITPNB - Canis familiaris [Reaction:R-MMU-1483087] PI is exchanged with PC by PITPNB - Mus musculus [Reaction:R-DDI-1483087] PI is exchanged with PC by PITPNB - Dictyostelium discoideum
output	[Complex:R-HSA-1524122] PC:PITPNB [Golgi membrane] [SimpleEntity:R-ALL-1524146] PI [Golgi membrane]
precedingEvent	[Reaction:R-HSA-1483229] PI:PITPNB is transported from the ER membrane to the Golgi membrane - Homo sapiens [Reaction:R-HSA-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Homo sapiens
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2247963] Wakelam, Michael, 2012-05-14 [InstanceEdit:9860910] Hill, David P, 2024-02-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1483087
summation	[Summation:1482877] At the Golgi membrane, phosphatidylinositol (PI) is exchange...

Referrals

(hasEvent)	[Pathway:R-HSA-1483196] PI and PC transport between ER and Golgi membranes
(precedingEvent)	[Reaction:R-HSA-1675883] PI is phosphorylated to PI4P by PI4KB at the Golgi membrane [Reaction:R-HSA-1675961] PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane [Reaction:R-HSA-1676185] PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane [Reaction:R-HSA-1483211] PC:PITPNB is transported from the Golgi membrane to the ER membrane

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