Reactome | CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane

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CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524061] diacylglycerol cholinephosphotransferase activity of CHPT1:Mg2+/Mn2+ [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482967] Williams, MG, 2011-08-12
crossReference	[DatabaseIdentifier:12667436] RHEA:32939
dbId	1482973
displayName	CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483191] Synthesis of PC - Homo sapiens
followingEvent	[Reaction:R-HSA-1483087] PI is exchanged with PC by PITPNB - Homo sapiens
input	[SimpleEntity:R-ALL-1524060] CDP-Cho [cytosol] [SimpleEntity:R-ALL-1524057] DAG [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1482959] Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine [LiteratureReference:1482937] Cloning, genomic organization, and characterization of a human cholinephosphotransferase [LiteratureReference:1482954] PC and PE synthesis: mixed micellar analysis of the cholinephosphotransferase and ethanolaminephosphotransferase activities of human choline/ethanolamine phosphotransferase 1 (CEPT1) [LiteratureReference:1482958] The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane
orthologousEvent	[Reaction:R-RNO-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Rattus norvegicus [Reaction:R-DRE-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Danio rerio [Reaction:R-CFA-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Canis familiaris [Reaction:R-SCE-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Saccharomyces cerevisiae [Reaction:R-SPO-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Schizosaccharomyces pombe [Reaction:R-BTA-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Bos taurus [Reaction:R-PFA-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Plasmodium falciparum [Reaction:R-SSC-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Sus scrofa [Reaction:R-CEL-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Caenorhabditis elegans [Reaction:R-DME-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Drosophila melanogaster [Reaction:R-XTR-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Xenopus tropicalis [Reaction:R-DDI-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Dictyostelium discoideum [Reaction:R-GGA-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Gallus gallus [Reaction:R-MMU-1482973] CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane - Mus musculus
output	[SimpleEntity:R-ALL-109395] CMP [cytosol] [SimpleEntity:R-ALL-429785] PC [Golgi membrane]
precedingEvent	[Reaction:R-HSA-1483081] PCho and CTP are condensed to CDP-Cho by PCYT1 dimer - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1482973
summation	[Summation:1482879] At the Golgi membrane, cholinephosphotransferase 1 (CHPT1) c...

Referrals

(hasEvent)	[Pathway:R-HSA-1483191] Synthesis of PC
(precedingEvent)	[Reaction:R-HSA-1483087] PI is exchanged with PC by PITPNB

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