Reactome | The ABCC family mediates organic anion transport

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The ABCC family mediates organic anion transport Show undefined attributes

authored	[InstanceEdit:1454911] Jassal, Bijay, 2011-07-19
catalystActivity	[CatalystActivity:1454941] ATPase-coupled transmembrane transporter activity of ABCCs [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:1454911] Jassal, Bijay, 2011-07-19
dbId	1454916
diseaseReaction	[FailedReaction:R-HSA-5690340] Defective ABCC6 does not transport organic anion from cytosol to extracellular region - Homo sapiens
displayName	The ABCC family mediates organic anion transport
edited	[InstanceEdit:1454911] Jassal, Bijay, 2011-07-19
eventOf	[Pathway:R-HSA-382556] ABC-family protein mediated transport - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-1454930] organic anion [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1454925] Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	The ABCC family mediates organic anion transport
orthologousEvent	[Reaction:R-PFA-1454916] The ABCC family mediates organic anion transport - Plasmodium falciparum [Reaction:R-SCE-1454916] The ABCC family mediates organic anion transport - Saccharomyces cerevisiae [Reaction:R-SPO-1454916] The ABCC family mediates organic anion transport - Schizosaccharomyces pombe [Reaction:R-DDI-1454916] The ABCC family mediates organic anion transport - Dictyostelium discoideum [Reaction:R-CEL-1454916] The ABCC family mediates organic anion transport - Caenorhabditis elegans [Reaction:R-DME-1454916] The ABCC family mediates organic anion transport - Drosophila melanogaster [Reaction:R-GGA-1454916] The ABCC family mediates organic anion transport - Gallus gallus [Reaction:R-XTR-1454916] The ABCC family mediates organic anion transport - Xenopus tropicalis [Reaction:R-DRE-1454916] The ABCC family mediates organic anion transport - Danio rerio [Reaction:R-SSC-1454916] The ABCC family mediates organic anion transport - Sus scrofa [Reaction:R-BTA-1454916] The ABCC family mediates organic anion transport - Bos taurus [Reaction:R-CFA-1454916] The ABCC family mediates organic anion transport - Canis familiaris [Reaction:R-RNO-1454916] The ABCC family mediates organic anion transport - Rattus norvegicus [Reaction:R-MMU-1454916] The ABCC family mediates organic anion transport - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-1454919] organic anion [extracellular region] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2011-09-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1502533] D'Eustachio, P, 2011-08-23
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1454916
summation	[Summation:1454918] The multidrug resistance associated protein (MRPs) subfamily...
updateTrackers	[UpdateTracker:9784025] Update Tracker - [Reaction:1454916] The ABCC family mediates organic anion transport - v55:[addLiteratureReference, modifyText] [UpdateTracker:9789027] Update Tracker - [Reaction:1454916] The ABCC family mediates organic anion transport - v39:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9784025] Update Tracker - [Reaction:1454916] The ABCC family mediates organic anion transport - v55:[addLiteratureReference, modifyText] [UpdateTracker:9789027] Update Tracker - [Reaction:1454916] The ABCC family mediates organic anion transport - v39:[modifyText]
(normalReaction)	[FailedReaction:R-HSA-5690340] Defective ABCC6 does not transport organic anion from cytosol to extracellular region
(hasEvent)	[Pathway:R-HSA-382556] ABC-family protein mediated transport

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