Reactome | 14-3-3 Binds p-S237-TBC1D1

Schema > Reaction > Entries

authored	[InstanceEdit:1449647] May, B, 2011-07-15
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1454712] May, B, 2011-07-17
dbId	1454689
displayName	14-3-3 Binds p-S237-TBC1D1
edited	[InstanceEdit:1449647] May, B, 2011-07-15
eventOf	[Pathway:R-HSA-1445148] Translocation of SLC2A4 (GLUT4) to the plasma membrane - Homo sapiens
followingEvent	[Reaction:R-HSA-2255343] RAB8A,10,13,14 exchange GDP for GTP - Homo sapiens
inferredFrom	[Reaction:R-MMU-1454713] 14-3-3 Binds Phosphorylated Tbc1d1 - Mus musculus
input	[DefinedSet:R-HSA-1445138] 14-3-3 dimer [cytosol] [EntityWithAccessionedSequence:R-HSA-1454673] p-S237-TBC1D1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:1454687] Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators [LiteratureReference:1454663] Exercise-induced TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	14-3-3 Binds p-S237-TBC1D1
output	[Complex:R-HSA-1454696] p-S237-TBC1D1:14-3-3 [cytosol]
precedingEvent	[Reaction:R-HSA-1454699] AMPK-alpha2 phosphorylates TBC1D1 - Homo sapiens
releaseDate	2012-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2454132] Klip, Amira, 2012-08-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1454689
summation	[Summation:1458482] TBC1D1 phosphorylated on serine-237 binds 14-3-3 proteins in...

(hasEvent)	[Pathway:R-HSA-1445148] Translocation of SLC2A4 (GLUT4) to the plasma membrane
(precedingEvent)	[Reaction:R-HSA-2255343] RAB8A,10,13,14 exchange GDP for GTP
(inferredTo)	[Reaction:R-MMU-1454713] 14-3-3 Binds Phosphorylated Tbc1d1

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