Reactome | Regulation of KIT signaling

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Regulation of KIT signaling Show undefined attributes

authored	[InstanceEdit:1433337] Garapati, P V, 2011-07-11
created	[InstanceEdit:1433555] Garapati, P V, 2011-07-11
dbId	1433559
displayName	Regulation of KIT signaling
edited	[InstanceEdit:1433337] Garapati, P V, 2011-07-11
eventOf	[Pathway:R-HSA-1433557] Signaling by SCF-KIT - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-1433508] PKC alpha interacts with and phosphorylates KIT - Homo sapiens [Reaction:R-HSA-205306] Interaction of SHP1 and KIT - Homo sapiens [Reaction:R-HSA-1433410] SOCS1 as a regulator of KIT signaling - Homo sapiens [Reaction:R-HSA-205319] Interaction of APS and p-KIT - Homo sapiens [Reaction:R-HSA-1433506] Phosphorylation of APS - Homo sapiens [Reaction:R-HSA-205244] Recruitment of CBL to KIT - Homo sapiens [Reaction:R-HSA-1470011] Downregulation of c-Kit signaling by SOCS6 - Homo sapiens [Reaction:R-HSA-1562640] LNK binds to p-KIT and inhibit downstream signaling - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2012-06-30
literatureReference	[LiteratureReference:1433399] Early signaling pathways activated by c-Kit in hematopoietic cells [LiteratureReference:1433408] Stem cell factor and its receptor c-Kit as targets for inflammatory diseases
maxDepth	2
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Regulation of KIT signaling
orthologousEvent	[Pathway:R-DME-1433559] Regulation of KIT signaling - Drosophila melanogaster [Pathway:R-CEL-1433559] Regulation of KIT signaling - Caenorhabditis elegans [Pathway:R-GGA-1433559] Regulation of KIT signaling - Gallus gallus [Pathway:R-XTR-1433559] Regulation of KIT signaling - Xenopus tropicalis [Pathway:R-DRE-1433559] Regulation of KIT signaling - Danio rerio [Pathway:R-SSC-1433559] Regulation of KIT signaling - Sus scrofa [Pathway:R-BTA-1433559] Regulation of KIT signaling - Bos taurus [Pathway:R-CFA-1433559] Regulation of KIT signaling - Canis familiaris [Pathway:R-RNO-1433559] Regulation of KIT signaling - Rattus norvegicus [Pathway:R-MMU-1433559] Regulation of KIT signaling - Mus musculus
releaseDate	2011-09-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1500883] R�nnstrand, Lars, 2011-08-22
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-1433559
summation	[Summation:1433560] SCF induced proliferation is negatively regulated by various...
updateTrackers	[UpdateTracker:9788625] Update Tracker - [Pathway:1433559] Regulation of KIT signaling - v41:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9788625] Update Tracker - [Pathway:1433559] Regulation of KIT signaling - v41:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-1433557] Signaling by SCF-KIT