Regulation of KIT signaling

Stable Identifier
R-HSA-1433559
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Regulation of KIT signaling
Click the image above or here to open this pathway in the Pathway Browser

SCF induced proliferation is negatively regulated by various proteins including SHP1, PKC, CBL, SOCS1, SOCS6 and LNK.

Literature References
PubMed ID Title Journal Year
10582339 Early signaling pathways activated by c-Kit in hematopoietic cells

Linnekin, D

Int J Biochem Cell Biol 1999
16483568 Stem cell factor and its receptor c-Kit as targets for inflammatory diseases

Reber, L, Da Silva, CA, Frossard, N

Eur J Pharmacol 2006
Participants
Events
Participant Of
hasEvent
Orthologous Events
Regulation of KIT signaling (Bos taurus)
Regulation of KIT signaling (Caenorhabditis elegans)
Regulation of KIT signaling (Canis familiaris)
Regulation of KIT signaling (Danio rerio)
Regulation of KIT signaling (Drosophila melanogaster)
Regulation of KIT signaling (Gallus gallus)
Regulation of KIT signaling (Mus musculus)
Regulation of KIT signaling (Rattus norvegicus)
Regulation of KIT signaling (Sus scrofa)
Regulation of KIT signaling (Xenopus tropicalis)
Authored
Garapati, P V  (2011-07-11)
Reviewed
Rönnstrand, L  (2011-08-22)
Created
Garapati, P V  (2011-07-11)