Reactome | MAD2 associates with the Mad1 kinetochore complex

Schema > Reaction > Entries

MAD2 associates with the Mad1 kinetochore complex Show undefined attributes

authored	[InstanceEdit:143430] Yen, T, 2004-05-05 00:00:00
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:143430] Yen, T, 2004-05-05 00:00:00
dbId	141431
displayName	MAD2 associates with the Mad1 kinetochore complex
eventOf	[Pathway:R-HSA-141444] Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal - Homo sapiens
followingEvent	[Reaction:R-HSA-141422] MAD2 converted to an inhibitory state via interaction with Mad1 - Homo sapiens
input	[Complex:R-HSA-141441] Mad1:kinetochore complex [cytosol] [EntityWithAccessionedSequence:R-HSA-141400] MAD2L1 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:143441] Mitotic checkpoint proteins HsMAD1 and HsMAD2 are associated with nuclear pore complexes in interphase
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	MAD2 associates with the Mad1 kinetochore complex
negativePrecedingEvent	[NegativePrecedingEvent:9749045] Incorrect Order: Release of activated MAD2 from kinetochores
orthologousEvent	[Reaction:R-GGA-141431] MAD2 associates with the Mad1 kinetochore complex - Gallus gallus [Reaction:R-XTR-141431] MAD2 associates with the Mad1 kinetochore complex - Xenopus tropicalis [Reaction:R-DRE-141431] MAD2 associates with the Mad1 kinetochore complex - Danio rerio [Reaction:R-SSC-141431] MAD2 associates with the Mad1 kinetochore complex - Sus scrofa [Reaction:R-BTA-141431] MAD2 associates with the Mad1 kinetochore complex - Bos taurus [Reaction:R-CFA-141431] MAD2 associates with the Mad1 kinetochore complex - Canis familiaris [Reaction:R-RNO-141431] MAD2 associates with the Mad1 kinetochore complex - Rattus norvegicus [Reaction:R-MMU-141431] MAD2 associates with the Mad1 kinetochore complex - Mus musculus
output	[Complex:R-HSA-141427] Kinetochore:Mad1:MAD2 Complex [cytosol]
precedingEvent	[Reaction:R-HSA-141409] Mad1 binds kinetochore - Homo sapiens
releaseDate	2005-02-01
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-141431
summation	[Summation:143357] Mad2 is recruited to the kinetochore through an interaction ...

Referrals

(hasEvent)	[Pathway:R-HSA-141444] Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
(precedingEvent)	[Reaction:R-HSA-141422] MAD2 converted to an inhibitory state via interaction with Mad1