Reactome | factor VII -> factor VIIa

Schema > Reaction > Entries

factor VII -> factor VIIa Show undefined attributes

authored	[InstanceEdit:140579] D'Eustachio, P, 2004-08-24 14:00:00
catalystActivity	[CatalystActivity:140768] serine-type endopeptidase activity of factor Xa [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:140579] D'Eustachio, P, 2004-08-24 14:00:00
dbId	140769
displayName	factor VII -> factor VIIa
eventOf	[Pathway:R-HSA-9769735] Initiation of coagulation cascade - Homo sapiens
followingEvent	[Reaction:R-HSA-140748] tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex - Homo sapiens
input	[Complex:R-HSA-8959612] Factor VII:Ca2+ [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:140773] Kinetics of human factor VII activation
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	factor VII -> factor VIIa activation of factor VII
orthologousEvent	[Reaction:R-GGA-140769] factor VII -> factor VIIa - Gallus gallus [Reaction:R-XTR-140769] factor VII -> factor VIIa - Xenopus tropicalis [Reaction:R-DRE-140769] factor VII -> factor VIIa - Danio rerio [Reaction:R-SSC-140769] factor VII -> factor VIIa - Sus scrofa [Reaction:R-BTA-140769] factor VII -> factor VIIa - Bos taurus [Reaction:R-CFA-140769] factor VII -> factor VIIa - Canis familiaris [Reaction:R-RNO-140769] factor VII -> factor VIIa - Rattus norvegicus [Reaction:R-MMU-140769] factor VII -> factor VIIa - Mus musculus
output	[Complex:R-HSA-140751] factor VIIa:Ca2+ [extracellular region]
precedingEvent	[Reaction:R-HSA-9822512] TF:FVIIa:FXa ->TF:FVIIa + FXa - Homo sapiens
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-140769
summation	[Summation:140772] Coagulation factor VII (FVII) circulates in plasma mostly in...
updateTrackers	[UpdateTracker:9781921] Update Tracker - [Reaction:140769] factor VII -> factor VIIa - v60:[add_removeInput] [UpdateTracker:9939659] Update Tracker - [Reaction:140769] factor VII -> factor VIIa - v92:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9781921] Update Tracker - [Reaction:140769] factor VII -> factor VIIa - v60:[add_removeInput] [UpdateTracker:9939659] Update Tracker - [Reaction:140769] factor VII -> factor VIIa - v92:[modifyText]
(hasEvent)	[Pathway:R-HSA-9769735] Initiation of coagulation cascade
(precedingEvent)	[Reaction:R-HSA-140748] tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex