Reactome | Transactivation of PMAIP1 (NOXA) by E2F1

Schema > BlackBoxEvent > Entries

Transactivation of PMAIP1 (NOXA) by E2F1 Show undefined attributes

category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:139911] Hardwick, JM, Tsujimoto, Y, 2004-08-09 19:10:09
dbId	140217
displayName	Transactivation of PMAIP1 (NOXA) by E2F1
eventOf	[Pathway:R-HSA-111448] Activation of NOXA and translocation to mitochondria - Homo sapiens
followingEvent	[Reaction:R-HSA-140216] Translocation of PMAIP1 (NOXA) to mitochondria - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-4331342] PMAIP1 Gene [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:141113] Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Transactivation of PMAIP1 (NOXA) by E2F1
output	[EntityWithAccessionedSequence:R-HSA-140215] PMAIP1 [cytosol]
precedingEvent	[Reaction:R-HSA-4331327] E2F1 binds PMAIP1 (NOXA) promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-159039] Positive gene expression regulation by 'E2F1:TFDP1:PMAIP1 Gene [nucleoplasm]'
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-140217
summation	[Summation:179352] E2F1 directly stimulates the transcription of PMAIP1 (NOXA) ...
updateTrackers	[UpdateTracker:9787214] Update Tracker - [BlackBoxEvent:140217] Transactivation of PMAIP1 (NOXA) by E2F1 - v46:[addInput, add_removeRegulator] [UpdateTracker:9787854] Update Tracker - [BlackBoxEvent:140217] Transactivation of PMAIP1 (NOXA) by E2F1 - v44:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9787214] Update Tracker - [BlackBoxEvent:140217] Transactivation of PMAIP1 (NOXA) by E2F1 - v46:[addInput, add_removeRegulator] [UpdateTracker:9787854] Update Tracker - [BlackBoxEvent:140217] Transactivation of PMAIP1 (NOXA) by E2F1 - v44:[modifyText]
(hasEvent)	[Pathway:R-HSA-111448] Activation of NOXA and translocation to mitochondria
(precedingEvent)	[Reaction:R-HSA-140216] Translocation of PMAIP1 (NOXA) to mitochondria

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