Transactivation of PMAIP1 (NOXA) by E2F1

Stable Identifier
R-HSA-140217
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
nucleoplasm
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Transactivation of PMAIP1 (NOXA) by E2F1
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E2F1 directly stimulates the transcription of PMAIP1 (NOXA) (Hershko and Ginsberg 2004).

Literature References
PubMed ID Title Journal Year
14684737 Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis

Hershko, T, Ginsberg, D

J Biol Chem 2004
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
E2F1:TFDP1:PMAIP1 Gene [nucleoplasm] (Homo sapiens)
Active Unit
E2F1:TFDP1,TFDP2 [nucleoplasm]
Created
Hardwick, JM  (2004-08-09)
Tsujimoto, Y  (2004-08-09)
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