Reactome | NR1D1 (REV-ERBA):heme:Corepressor [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-5663261] NR1D1:heme:Corepressors:ELOVL3 gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-5663262] NR1D1:heme:Corepressors:NR1D1 gene [nucleoplasm] - Homo sapiens
created	[InstanceEdit:1368132] May, B, 2011-06-29
dbId	1368079
displayName	NR1D1 (REV-ERBA):heme:Corepressor [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-442464] HDAC3 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-442501] NCOR1 [nucleoplasm] [Complex:R-HSA-1368127] NR1D1 (REV-ERBA):heme [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:1368067] Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction [LiteratureReference:549400] The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene [LiteratureReference:1368128] Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways [LiteratureReference:549530] Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta
maxDepth	3
modified	[InstanceEdit:5663276] May, Bruce, 2015-01-16
name	NR1D1 (REV-ERBA):heme:Corepressor
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1368079
updateTrackers	[UpdateTracker:9891477] Update Tracker - [Complex:1368079] NR1D1 (REV-ERBA):heme:Corepressor [nucleoplasm] - v52:[addLiteratureReference, removeHasComponent]

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