Reactome | NR1D1:heme:Corepressors:NPAS2 gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5663250] May, Bruce, 2015-01-16
dbId	5663274
displayName	NR1D1:heme:Corepressors:NPAS2 gene [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-5640176] NPAS2 gene [nucleoplasm] [Complex:R-HSA-1368079] NR1D1 (REV-ERBA):heme:Corepressor [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-5667080] Nr1d1:heme:Corepressors:Npas2 gene [nucleoplasm] - Mus musculus
isChimeric	false
literatureReference	[LiteratureReference:1368152] Characterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target gene
maxDepth	4
modified	[InstanceEdit:5667097] May, Bruce, 2015-01-23
name	NR1D1:heme:Corepressors:NPAS2 gene
negativelyRegulates	[NegativeGeneExpressionRegulation:R-HSA-1368161] Negative gene expression regulation by 'NR1D1:heme:Corepressors:NPAS2 gene [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-5663245] NR1D1 (REV-ERBA) binds heme, the NPAS2 gene, and recruits corepressors - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5663274

(output)	[Reaction:R-HSA-5663245] NR1D1 (REV-ERBA) binds heme, the NPAS2 gene, and recruits corepressors
(regulator)	[NegativeGeneExpressionRegulation:R-HSA-1368161] Negative gene expression regulation by 'NR1D1:heme:Corepressors:NPAS2 gene [nucleoplasm]'

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