NR1D1 (REV-ERBA):heme:Corepressor [nucleoplasm]

Stable Identifier
Homo sapiens
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
18006707 Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

Yin, L, Wu, N, Curtin, JC, Qatanani, M, Szwergold, NR, Reid, RA, Waitt, GM, Parks, DJ, Pearce, KH, Wisely, GB, Lazar, MA

Science 2007
20581824 Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction

Phelan, CA, Gampe RT, Jr, Lambert, MH, Parks, DJ, Montana, V, Bynum, J, Broderick, TM, Hu, X, Williams, SP, Nolte, RT, Lazar, MA

Nat Struct Mol Biol 2010
18037887 Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta

Raghuram, S, Stayrook, KR, Huang, P, Rogers, PM, Nosie, AK, McClure, DB, Burris, LL, Khorasanizadeh, S, Burris, TP, Rastinejad, F

Nat Struct Mol Biol 2007
15761026 The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene

Yin, L, Lazar, MA

Mol Endocrinol 2005
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