Reactome | Negative regulation by 'GHBP:GHR [plasma membrane]'

Schema > NegativeRegulation > Entries

created	[InstanceEdit:1362494] Jupe, S, 2011-06-10
dbId	1362495
displayName	Negative regulation by 'GHBP:GHR [plasma membrane]'
modified	[InstanceEdit:9733355] Wu, Guanming, 2021-06-04
regulatedEntity	[Reaction:R-HSA-982775] Growth hormone receptor dimerizes - Homo sapiens
regulator	[Complex:R-HSA-1362481] GHBP:GHR [plasma membrane]
schemaClass	NegativeRegulation
stId	R-HSA-1362495

(regulation)	[RegulationReference:9642925] Negative regulation by 'GHBP:GHR [plasma membrane]' A short isoform of the human growth hormone receptor functions as a dominant negative inhibitor of the full-length receptor and generates large amounts of binding protein
(regulatedBy)	[Reaction:R-HSA-982775] Growth hormone receptor dimerizes

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