Reactome | FRAT1,2:GSK3beta [cytosol]

Schema > Complex > Entries

FRAT1,2:GSK3beta [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1226048] May, B, 2011-03-07
dbId	1226052
displayName	FRAT1,2:GSK3beta [cytosol]
hasComponent	[DefinedSet:R-HSA-1226058] FRAT1,2 [cytosol] [EntityWithAccessionedSequence:R-HSA-2997551] GSK3B [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-1226052] FRAT1,2:GSK3beta [cytosol] - Mus musculus [Complex:R-RNO-1226052] FRAT1,2:GSK3beta [cytosol] - Rattus norvegicus [Complex:R-CFA-1226052] FRAT1,2:GSK3beta [cytosol] - Canis familiaris [Complex:R-BTA-1226052] FRAT1,2:GSK3beta [cytosol] - Bos taurus [Complex:R-SSC-1226052] FRAT1,2:GSK3beta [cytosol] - Sus scrofa [Complex:R-DRE-1226052] FRAT1,2:GSK3beta [cytosol] - Danio rerio [Complex:R-XTR-1226052] FRAT1,2:GSK3beta [cytosol] - Xenopus tropicalis [Complex:R-GGA-1226052] FRAT1,2:GSK3beta [cytosol] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:453065] Characterization and tissue-specific expression of human GSK-3-binding proteins FRAT1 and FRAT2 [LiteratureReference:453034] Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway
maxDepth	3
modified	[InstanceEdit:5262813] May, B, 2014-02-07
name	FRAT1,2:GSK3beta
negativelyRegulates	[NegativeRegulation:R-HSA-1226064] Negative regulation by 'FRAT1,2:GSK3beta [cytosol]' [NegativeRegulation:R-HSA-1226062] Negative regulation by 'FRAT1,2:GSK3beta [cytosol]' [NegativeRegulation:R-HSA-1226061] Negative regulation by 'FRAT1,2:GSK3beta [cytosol]'
producedByEvent	[Reaction:R-HSA-5323526] FRAT proteins bind GSK3beta - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1226052
updateTrackers	[UpdateTracker:9877755] Update Tracker - [Complex:1226052] FRAT1,2:GSK3beta [cytosol] - v44:[add_removeHasComponent] [UpdateTracker:9889088] Update Tracker - [Complex:1226052] FRAT1,2:GSK3beta [cytosol] - v48:[modifyName, updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9877755] Update Tracker - [Complex:1226052] FRAT1,2:GSK3beta [cytosol] - v44:[add_removeHasComponent] [UpdateTracker:9889088] Update Tracker - [Complex:1226052] FRAT1,2:GSK3beta [cytosol] - v48:[modifyName, updateContainedComponent]
(regulator)	[NegativeRegulation:R-HSA-1226064] Negative regulation by 'FRAT1,2:GSK3beta [cytosol]' [NegativeRegulation:R-HSA-1226062] Negative regulation by 'FRAT1,2:GSK3beta [cytosol]' [NegativeRegulation:R-HSA-1226061] Negative regulation by 'FRAT1,2:GSK3beta [cytosol]'
(output)	[Reaction:R-HSA-5323526] FRAT proteins bind GSK3beta

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