Reactome | EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1225980] Orlic-Milacic, Marija, 2011-03-03
dbId	1225979
displayName	EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane]
hasComponent	[DefinedSet:R-ALL-1216522] Covalent EGFR tyrosine kinase inhibitors [cytosol] [Complex:R-HSA-9624420] EGF-like ligands:EGFR dimer [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
isChimeric	false
maxDepth	5
modified	[InstanceEdit:9624439] Rothfels, Karen, 2018-10-11
name	EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs EGF:EGFR Dimer:irrevTKIs
producedByEvent	[Reaction:R-HSA-1225978] Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1225979
updateTrackers	[UpdateTracker:9872993] Update Tracker - [Complex:1225979] EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane] - v42:[updateContainedComponent] [UpdateTracker:9899786] Update Tracker - [Complex:1225979] EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane] - v67:[add_removeHasComponent, modifyName] [UpdateTracker:9871969] Update Tracker - [Complex:1225979] EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane] - v41:[removeCompartment, updateContainedComponent]

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