Reactome | Iron is reduced and separates from mycobactin

Schema > Reaction > Entries

Iron is reduced and separates from mycobactin Show undefined attributes

authored	[InstanceEdit:1222281] Stephan, R, 2011-01-10
catalystActivity	[CatalystActivity:1222683] FMN reductase (NADPH) activity of IrtAB:Rv2895c [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:1222482] Jassal, B, 2011-02-28
crossReference	[DatabaseIdentifier:12020769] Mondo:0018076
dbId	1222399
disease	[Disease:1660556] tuberculosis
displayName	Iron is reduced and separates from mycobactin
edited	[InstanceEdit:1222482] Jassal, B, 2011-02-28
eventOf	[Pathway:R-HSA-1222449] Mtb iron assimilation by chelation - Homo sapiens
inferredFrom	[Reaction:R-ECO-1222667] Iron is reduced and separates from enterobactin - Escherichia coli
input	2 × [Complex:R-ALL-5607579] Mycobactin:Fe3+ [cytosol] 2 × [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isChimeric	false
isInDisease	true
isInferred	true
literatureReference	[LiteratureReference:1222592] Mechanistic insights into a novel exporter-importer system of Mycobacterium tuberculosis unravel its role in trafficking of iron
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Iron is reduced and separates from mycobactin
output	2 × [SimpleEntity:R-ALL-71067] Fe2+ [cytosol] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol] 2 × [SimpleEntity:R-ALL-1222609] Mycobactin [cytosol] 2 × [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent	[Reaction:R-HSA-1222597] Loaded mycobactin gets imported - Homo sapiens
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2213261] Warner, D, 2012-04-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1222399
summation	[Summation:1222752] The IrtA transporter has a flavin reductase domain very much...
updateTrackers	[UpdateTracker:9788267] Update Tracker - [Reaction:1222399] Iron is reduced and separates from mycobactin - v43:[addOutput] [UpdateTracker:9786300] Update Tracker - [Reaction:1222399] Iron is reduced and separates from mycobactin - v50:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9788267] Update Tracker - [Reaction:1222399] Iron is reduced and separates from mycobactin - v43:[addOutput] [UpdateTracker:9786300] Update Tracker - [Reaction:1222399] Iron is reduced and separates from mycobactin - v50:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-1222449] Mtb iron assimilation by chelation
(inferredTo)	[Reaction:R-ECO-1222667] Iron is reduced and separates from enterobactin

Cite Us!