Reactome | Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs [plasma membrane]

Schema > CandidateSet > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-1809168] Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] - Homo sapiens [Complex:R-HSA-1809164] EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] - Homo sapiens
created	[InstanceEdit:1182981] Orlic-Milacic, Marija, 2011-02-09
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	1182982
disease	[Disease:1500689] cancer
displayName	Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs [plasma membrane]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-1996335] p-6Y-EGFR D770_N771insNPG [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1996342] p-6Y-EGFR N771_H773dup [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1996343] p-6Y-EGFR A767_V769dup [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1996346] p-6Y-EGFR K739_I744dup [plasma membrane] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-1182985] p-6Y-EGFR E746_A750del;T790M [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1182984] p-6Y-EGFR L858R;T790M [plasma membrane] - Homo sapiens
inDisease	true
maxDepth	2
modified	[InstanceEdit:1996378] Orlic-Milacic, Marija, 2011-11-19
name	Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-1182982

(hasComponent)

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