Reactome | Fyn/Lyn-mediated phosphorylation of FcR1 gamma

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Fyn/Lyn-mediated phosphorylation of FcR1 gamma Show undefined attributes

catalystActivity	[CatalystActivity:139843] protein tyrosine kinase activity of GPVI:FceRI gamma:FYN:LYN:Collagen type I [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:141659] de Bono, B, Pace, N.P., Farndale, R, 2004-09-25 17:06:19
dbId	114600
displayName	Fyn/Lyn-mediated phosphorylation of FcR1 gamma
eventOf	[Pathway:R-HSA-114604] GPVI-mediated activation cascade - Homo sapiens
followingEvent	[Reaction:R-HSA-139842] Binding of Syk tyrosine kinase - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-434812] GPVI:FceRI gamma:FYN:LYN:Collagen type I [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:139987] A collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma2 in platelets independent of the integrin alpha2beta1
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	Fyn/Lyn-mediated phosphorylation of FcR1 gamma
orthologousEvent	[Reaction:R-XTR-114600] Fyn/Lyn-mediated phosphorylation of FcR1 gamma - Xenopus tropicalis [Reaction:R-BTA-114600] Fyn/Lyn-mediated phosphorylation of FcR1 gamma - Bos taurus [Reaction:R-CFA-114600] Fyn/Lyn-mediated phosphorylation of FcR1 gamma - Canis familiaris [Reaction:R-RNO-114600] Fyn/Lyn-mediated phosphorylation of FcR1 gamma - Rattus norvegicus [Reaction:R-MMU-114600] Fyn/Lyn-mediated phosphorylation of FcR1 gamma - Mus musculus
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-434822] GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I [plasma membrane]
precedingEvent	[Reaction:R-HSA-114577] Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-114600
summation	[Summation:179184] At the beginning of this reaction, 1 molecule of 'GP VI:Fc E...
updateTrackers	[UpdateTracker:9791404] Update Tracker - [Reaction:114600] Fyn/Lyn-mediated phosphorylation of FcR1 gamma - v30:[add_removeInput, add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9791404] Update Tracker - [Reaction:114600] Fyn/Lyn-mediated phosphorylation of FcR1 gamma - v30:[add_removeInput, add_removeOutput]
(hasEvent)	[Pathway:R-HSA-114604] GPVI-mediated activation cascade
(precedingEvent)	[Reaction:R-HSA-139842] Binding of Syk tyrosine kinase

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