Fyn/Lyn-mediated phosphorylation of FcR1 gamma

Stable Identifier
R-HSA-114600
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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At the beginning of this reaction, 1 molecule of 'GP VI:Fc Epsilon R1 gamma:Collagen IV complex', and 1 molecule of 'ATP' are present. At the end of this reaction, 1 molecule of 'ADP', and 1 molecule of 'GP VI:phosphorylated Fc Epsilon R1 gamma:Collagen IV complex' are present.

This reaction is mediated by the 'protein-tyrosine kinase activity' of 'GP VI: Fc Epsilon R1 gamma: Collagen IV: SRC'.

Literature References
PubMed ID Title Journal Year
9028946 A collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma2 in platelets independent of the integrin alpha2beta1

Farndale, RW, Morton, LF, Watson, SP, Barnes, MJ, Gibbins, JM, Asselin, J, Lee, YH, Achison, M

Blood 1997
Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of GPVI:FceRI gamma:FYN:LYN:Collagen type I [plasma membrane]

Orthologous Events
Created
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