Reactome | Hypophosphorylation of RNA Pol II CTD by FCP1P protein

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Hypophosphorylation of RNA Pol II CTD by FCP1P protein Show undefined attributes

authored	[InstanceEdit:112380] Gopinathrao, G, 2004-04-28 10:54:00
catalystActivity	[CatalystActivity:113432] phosphoprotein phosphatase activity of CTDP1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:75957] Conaway, JW, Conaway, RC, 2003-09-11
dbId	112383
displayName	Hypophosphorylation of RNA Pol II CTD by FCP1P protein
eventOf	[Pathway:R-HSA-113418] Formation of the Early Elongation Complex - Homo sapiens
followingEvent	[Reaction:R-HSA-113407] DSIF complex binds to RNA Pol II (hypophosphorylated) - Homo sapiens
input	[Complex:R-HSA-77089] capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-113416] CTDP1 [nucleoplasm] [Complex:R-HSA-109634] TFIIH [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:113810] FCP1, a phosphatase specific for the heptapeptide repeat of the largest subunit of RNA polymerase II, stimulates transcription elongation. [LiteratureReference:6814946] FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Hypophosphorylation of RNA Pol II CTD by FCP1P protein
orthologousEvent	[BlackBoxEvent:R-HSA-6814554] Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene - Homo sapiens [Reaction:R-HSA-167072] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Homo sapiens [Reaction:R-PFA-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Plasmodium falciparum [Reaction:R-SCE-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Saccharomyces cerevisiae [Reaction:R-SPO-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Schizosaccharomyces pombe [Reaction:R-DDI-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Dictyostelium discoideum [Reaction:R-CEL-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Caenorhabditis elegans [Reaction:R-DME-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Drosophila melanogaster [Reaction:R-XTR-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Xenopus tropicalis [Reaction:R-DRE-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Danio rerio [Reaction:R-SSC-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Sus scrofa [Reaction:R-BTA-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Bos taurus [Reaction:R-CFA-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Canis familiaris [Reaction:R-RNO-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Rattus norvegicus [Reaction:R-MMU-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Mus musculus
output	[Complex:R-HSA-113715] RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] [Complex:R-HSA-109634] TFIIH [nucleoplasm]
precedingEvent	[Reaction:R-HSA-77095] Recognition and binding of the mRNA cap by the cap-binding complex - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-112383
summation	[Summation:112393] FCP1 dephosphorylates RNAP II in ternary elongation complexe...
updateTrackers	[UpdateTracker:9784135] Update Tracker - [Reaction:112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - v54:[addLiteratureReference] [UpdateTracker:9783605] Update Tracker - [Reaction:112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - v56:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9784135] Update Tracker - [Reaction:112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - v54:[addLiteratureReference] [UpdateTracker:9783605] Update Tracker - [Reaction:112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - v56:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-113418] Formation of the Early Elongation Complex
(precedingEvent)	[Reaction:R-HSA-113407] DSIF complex binds to RNA Pol II (hypophosphorylated)

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