Reactome | Neurotransmitter clearance

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Neurotransmitter clearance Show undefined attributes

authored	[InstanceEdit:210542] Mahajan, SS, 2008-01-14 16:01:52
created	[InstanceEdit:112300] Joshi-Tope, G, 2004-04-22 09:35:00
dbId	112311
diseasePathways	[Pathway:R-HSA-5619081] Defective neurotransmitter clearance by SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) - Homo sapiens
displayName	Neurotransmitter clearance
edited	[InstanceEdit:210542] Mahajan, SS, 2008-01-14 16:01:52
eventOf	[Pathway:R-HSA-112315] Transmission across Chemical Synapses - Homo sapiens
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-372519] AcCho is hydrolyzed to Cho and acetate by ACHE - Homo sapiens [Reaction:R-HSA-9634834] ACHEIs bind ACHE - Homo sapiens [Reaction:R-HSA-374919] Noradrenaline clearance from the synaptic cleft - Homo sapiens [Pathway:R-HSA-379401] Dopamine clearance from the synaptic cleft - Homo sapiens [Pathway:R-HSA-380615] Serotonin clearance from the synaptic cleft - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-06-09
maxDepth	4
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Neurotransmitter clearance
orthologousEvent	[Pathway:R-PFA-112311] Neurotransmitter clearance - Plasmodium falciparum [Pathway:R-SCE-112311] Neurotransmitter clearance - Saccharomyces cerevisiae [Pathway:R-SPO-112311] Neurotransmitter clearance - Schizosaccharomyces pombe [Pathway:R-DDI-112311] Neurotransmitter clearance - Dictyostelium discoideum [Pathway:R-CEL-112311] Neurotransmitter clearance - Caenorhabditis elegans [Pathway:R-DME-112311] Neurotransmitter clearance - Drosophila melanogaster [Pathway:R-GGA-112311] Neurotransmitter clearance - Gallus gallus [Pathway:R-XTR-112311] Neurotransmitter clearance - Xenopus tropicalis [Pathway:R-DRE-112311] Neurotransmitter clearance - Danio rerio [Pathway:R-SSC-112311] Neurotransmitter clearance - Sus scrofa [Pathway:R-BTA-112311] Neurotransmitter clearance - Bos taurus [Pathway:R-CFA-112311] Neurotransmitter clearance - Canis familiaris [Pathway:R-RNO-112311] Neurotransmitter clearance - Rattus norvegicus [Pathway:R-MMU-112311] Neurotransmitter clearance - Mus musculus
precedingEvent	[Pathway:R-HSA-112310] Neurotransmitter release cycle - Homo sapiens
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:386898] Restituito, S, 2008-11-27 12:38:49
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-112311
summation	[Summation:349559] Neurotransmitter released in the synaptic cleft binds to spe...
updateTrackers	[UpdateTracker:9790236] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v34:[updateContainedPathway] [UpdateTracker:9778496] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v68:[updateContainedRLE] [UpdateTracker:9791258] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v31:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9791762] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v26:[addHasEvent] [UpdateTracker:9776874] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v74:[updateContainedPathway] [UpdateTracker:9788914] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v39:[updateContainedRLE] [UpdateTracker:9783036] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v57:[updateContainedPathway] [UpdateTracker:9788635] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v41:[updateContainedRLE] [UpdateTracker:9781526] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v60:[updateContainedPathway] [UpdateTracker:9779282] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v66:[modifyText] [UpdateTracker:9791675] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v27:[addHasEvent] [UpdateTracker:9777069] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v73:[addHasEvent] [UpdateTracker:9791457] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v30:[updateIndirectRLE] [UpdateTracker:9774773] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v81:[updateContainedPathway]

Referrals

(updatedInstance)	[UpdateTracker:9790236] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v34:[updateContainedPathway] [UpdateTracker:9778496] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v68:[updateContainedRLE] [UpdateTracker:9791258] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v31:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9791762] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v26:[addHasEvent] [UpdateTracker:9776874] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v74:[updateContainedPathway] [UpdateTracker:9788914] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v39:[updateContainedRLE] [UpdateTracker:9783036] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v57:[updateContainedPathway] [UpdateTracker:9788635] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v41:[updateContainedRLE] [UpdateTracker:9781526] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v60:[updateContainedPathway] [UpdateTracker:9779282] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v66:[modifyText] [UpdateTracker:9791675] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v27:[addHasEvent] [UpdateTracker:9777069] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v73:[addHasEvent] [UpdateTracker:9791457] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v30:[updateIndirectRLE] [UpdateTracker:9774773] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v81:[updateContainedPathway]
(hasEvent)	[Pathway:R-HSA-112315] Transmission across Chemical Synapses
(normalPathway)	[Pathway:R-HSA-5619081] Defective neurotransmitter clearance by SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)

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