Reactome | Nonsense-Mediated Decay (NMD)

Schema > Pathway > Entries

Nonsense-Mediated Decay (NMD) Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10827069
displayName	Nonsense-Mediated Decay (NMD)
eventOf	[TopLevelPathway:R-GGA-8953854] Metabolism of RNA - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:21780] nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-GGA-975957] Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) - Gallus gallus [Pathway:R-GGA-975956] Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) - Gallus gallus
inferredFrom	[Pathway:R-HSA-927802] Nonsense-Mediated Decay (NMD) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Nonsense-Mediated Decay (NMD)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-927802
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-GGA-8953854] Metabolism of RNA
(hasEncapsulatedEvent)	[Pathway:R-GGA-376176] Signaling by ROBO receptors
(inferredTo)	[Pathway:R-HSA-927802] Nonsense-Mediated Decay (NMD)

Cite Us!