Reactome | ASPG hydrolyses L-Asn to L-Asp

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ASPG hydrolyses L-Asn to L-Asp Show undefined attributes

catalystActivity	[CatalystActivity:10799621] asparaginase activity of ASPG [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10799623
displayName	ASPG hydrolyses L-Asn to L-Asp
eventOf	[Pathway:R-GGA-8963693] Aspartate and asparagine metabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-6787757] PXLP-K333-GADL1 decarboxylates acidic AAs - Gallus gallus [Reaction:R-GGA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Gallus gallus
inferredFrom	[Reaction:R-HSA-6797627] ASPG hydrolyses L-Asn to L-Asp - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29642] L-Asn [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ASPG hydrolyses L-Asn to L-Asp H2O + L-asparagine => L-aspartate + NH4(+)
output	[SimpleEntity:R-ALL-29448] L-Asp [cytosol] [SimpleEntity:R-ALL-31633] NH4+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-6797627
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-8963693] Aspartate and asparagine metabolism
(precedingEvent)	[Reaction:R-GGA-6787757] PXLP-K333-GADL1 decarboxylates acidic AAs [Reaction:R-GGA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp
(inferredTo)	[Reaction:R-HSA-6797627] ASPG hydrolyses L-Asn to L-Asp

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