Reactome | POLN [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-GGA-6786156] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-6786155] POLN binds ICL-DNA - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10798643
displayName	POLN [nucleoplasm]
endCoordinate	900
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-6786153] POLN [nucleoplasm] - Homo sapiens
maxDepth	1
name	POLN POLN A0A8V0Z9E4
producedByEvent	[BlackBoxEvent:R-GGA-6786166] Translesion synthesis across unhooked ICL by POLN - Gallus gallus
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8V0Z9E4] UniProt:A0A8V0Z9E4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49591] Gallus gallus
stId	R-GGA-6786153
startCoordinate	1

(output)	[BlackBoxEvent:R-GGA-6786166] Translesion synthesis across unhooked ICL by POLN
(activeUnit)	[CatalystActivity:10798648] DNA-directed DNA polymerase activity of MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm]
(input)	[Reaction:R-GGA-6786155] POLN binds ICL-DNA
(hasComponent)	[Complex:R-GGA-6786156] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-6786153] POLN [nucleoplasm]

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