Reactome | CASP9(1-416) [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-6804623] CASP9(1-416) dimer [cytosol] - Gallus gallus [Complex:R-GGA-6804623] CASP9(1-416) dimer [cytosol] - Gallus gallus [Complex:R-GGA-6805422] CASP9:CARD [cytosol] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-6805426] CARD8 binds CASP9(1-416) - Gallus gallus [Reaction:R-GGA-114256] CYCS:APAF1 binds procaspase-9 - Gallus gallus [Reaction:R-GGA-114256] CYCS:APAF1 binds procaspase-9 - Gallus gallus [Reaction:R-GGA-114256] CYCS:APAF1 binds procaspase-9 - Gallus gallus [Reaction:R-GGA-114256] CYCS:APAF1 binds procaspase-9 - Gallus gallus [Reaction:R-GGA-198621] AKT phosphorylates caspase-9 - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10739124
displayName	CASP9(1-416) [cytosol]
endCoordinate	416
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-57033] CASP9(1-416) [cytosol] - Homo sapiens
maxDepth	1
name	CASP9(1-416) A0A8V0ZGA5
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8V0ZGA5] UniProt:A0A8V0ZGA5
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49591] Gallus gallus
stId	R-GGA-57033
startCoordinate	1

(input)	[Reaction:R-GGA-198621] AKT phosphorylates caspase-9 [Reaction:R-GGA-6805426] CARD8 binds CASP9(1-416) [Reaction:R-GGA-114256] CYCS:APAF1 binds procaspase-9
(hasComponent)	[Complex:R-GGA-6805422] CASP9:CARD [cytosol] [Complex:R-GGA-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] [Complex:R-GGA-6804623] CASP9(1-416) dimer [cytosol]
(activeUnit)	[CatalystActivity:10739148] cysteine-type endopeptidase activity of APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-57033] CASP9(1-416) [cytosol]

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