Reactome | AKT phosphorylates caspase-9

Schema > Reaction > Entries

AKT phosphorylates caspase-9 Show undefined attributes

catalystActivity	[CatalystActivity:10741950] protein serine/threonine kinase activity of p-T,p-S-AKT [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10746899
displayName	AKT phosphorylates caspase-9
eventOf	[Pathway:R-GGA-198323] AKT phosphorylates targets in the cytosol - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:172430] phosphatidylinositol 3-kinase/protein kinase B signal transduction
inferredFrom	[Reaction:R-HSA-198621] AKT phosphorylates caspase-9 - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-GGA-57033] CASP9(1-416) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AKT phosphorylates caspase-9
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-GGA-198636] phospho-p-S196-CASP9(1-416) [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-198621
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-198323] AKT phosphorylates targets in the cytosol
(inferredTo)	[Reaction:R-HSA-198621] AKT phosphorylates caspase-9

Cite Us!