Reactome | Ubiquitinated DVL1 is degraded by the proteasome

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Ubiquitinated DVL1 is degraded by the proteasome Show undefined attributes

catalystActivity	[CatalystActivity:10732838] endopeptidase activity of 26S proteasome [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10787387
displayName	Ubiquitinated DVL1 is degraded by the proteasome
eventOf	[Pathway:R-GGA-4641258] Degradation of DVL - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-4641260] Ubiquitinated DVL1 is degraded by the proteasome - Homo sapiens
input	[Complex:R-GGA-4641160] ub-DVL1:HECW1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Ubiquitinated DVL1 is degraded by the proteasome
output	[EntityWithAccessionedSequence:R-GGA-4641156] HECW1 [cytosol] [DefinedSet:R-GGA-113595] Ub [cytosol]
precedingEvent	[Reaction:R-GGA-4641159] DVL1 is ubiquitinated by HECW1 - Gallus gallus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49591] Gallus gallus
stId	R-GGA-4641260
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-4641258] Degradation of DVL
(inferredTo)	[BlackBoxEvent:R-HSA-4641260] Ubiquitinated DVL1 is degraded by the proteasome

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