Reactome | inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+

Schema > Reaction > Entries

inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ Show undefined attributes

authored	[InstanceEdit:421217] D'Eustachio, P, 2009-05-16 16:42:13
catalystActivity	[CatalystActivity:421215] IMP dehydrogenase activity of IMPDH2 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:421216] D'Eustachio, P, 2009-05-16 16:44:05
dbId	421222
displayName	inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+
edited	[InstanceEdit:421217] D'Eustachio, P, 2009-05-16 16:42:13
eventOf	[Pathway:R-GGA-421223] De novo synthesis of GMP - Gallus gallus
followingEvent	[Reaction:R-GGA-421218] xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate - Gallus gallus
inferredFrom	[Reaction:R-HSA-73794] IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29602] IMP [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol] [SimpleEntity:R-ALL-111584] XMP [cytosol]
precedingEvent	[Reaction:R-GGA-419253] 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) <=> inosine 5'-monophosphate + H2O - Gallus gallus
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-421222
summation	[Summation:421219] Cytosolic IMPDH2 (inosine-5'-monophosphate dehydrogenase 2) ...

Referrals

(precedingEvent)	[Reaction:R-GGA-421218] xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate
(hasEvent)	[Pathway:R-GGA-421223] De novo synthesis of GMP
(inferredTo)	[Reaction:R-HSA-73794] IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]

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