inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+

Stable Identifier
R-GGA-421222
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
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inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic IMPDH2 (inosine-5'-monophosphate dehydrogenase 2) catalyzes the reaction of inosine 5'-monophosphate (IMP), NAD+ and H2O to form xanthosine 5'-monophosphate (XMP) and NADH + H+. Chicken IMPDH2 has been identified only as the inferred product of a cDNA clone; this reaction has been inferred from its better studied human counterpart.

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Catalyst Activity

IMP dehydrogenase activity of IMPDH2 [cytosol]

Physical Entity
IMPDH2 [cytosol] (Gallus gallus)
Activity
IMP dehydrogenase activity (GO:0003938)
Inferred From
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Homo sapiens)
Authored
D'Eustachio, P  (2009-05-16)
Created
D'Eustachio, P  (2009-05-16)
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