Reactome | L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate

Schema > Reaction > Entries

L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate Show undefined attributes

authored	[InstanceEdit:419450] D'Eustachio, P, 2009-05-01 14:10:50
catalystActivity	[CatalystActivity:419445] carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity of CAD hexamer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:419447] D'Eustachio, P, 2009-04-30 22:31:59
dbId	419440
displayName	L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate
edited	[InstanceEdit:419450] D'Eustachio, P, 2009-05-01 14:10:50
eventOf	[Pathway:R-GGA-419469] Pyrimidine metabolism: de novo synthesis of UMP - Gallus gallus
followingEvent	[Reaction:R-GGA-419451] carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate - Gallus gallus
inferredFrom	[Reaction:R-HSA-73577] CAD hexamer transforms L-Gln to CAP - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-111627] HCO3- [cytosol] [SimpleEntity:R-ALL-29472] L-Gln [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-111647] CAP [cytosol] [SimpleEntity:R-ALL-29404] L-Glu [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-419440
summation	[Summation:419437] The carbamoyl-phosphate synthase (glutamine-hydrolyzing) act...

Referrals

(hasEvent)	[Pathway:R-GGA-419469] Pyrimidine metabolism: de novo synthesis of UMP
(precedingEvent)	[Reaction:R-GGA-419451] carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate
(inferredTo)	[Reaction:R-HSA-73577] CAD hexamer transforms L-Gln to CAP

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