Reactome | pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+

Schema > Reaction > Entries

pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ Show undefined attributes

authored	[InstanceEdit:376875] D'Eustachio, P, 2008-09-10 19:15:11
catalystActivity	[CatalystActivity:373175] dihydrolipoyl dehydrogenase (NADH) activity of pyruvate dehydrogenase complex [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:373179] D'Eustachio, P, 2008-07-14 19:42:38
dbId	373177
displayName	pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+
edited	[InstanceEdit:376875] D'Eustachio, P, 2008-09-10 19:15:11
eventOf	[Pathway:R-GGA-373920] Pyruvate metabolism - Gallus gallus
followingEvent	[Reaction:R-GGA-373006] acetyl-CoA + H2O + oxaloacetate => citrate + CoA - Gallus gallus
input	[SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix] [SimpleEntity:R-ALL-113526] NAD+ [mitochondrial matrix] [SimpleEntity:R-ALL-113557] PYR [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:69983] Structure-function relationships in dihydrolipoamide acyltransferases
maxDepth	1
modified	[InstanceEdit:9910890] Matthews, Lisa, 2024-05-22
name	pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+
output	[SimpleEntity:R-ALL-113559] Ac-CoA [mitochondrial matrix] [SimpleEntity:R-ALL-29376] CO2 [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-29362] NADH [mitochondrial matrix]
precedingEvent	[Reaction:R-GGA-372359] pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] - Gallus gallus
releaseDate	2009-06-01
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-373177
summation	[Summation:373180] Mitochondrial pyruvate dehydrogenase complex catalyzes the r...
updateTrackers	[UpdateTracker:9911013] Update Tracker - [Reaction:373177] pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ - v89:[addLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9911013] Update Tracker - [Reaction:373177] pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ - v89:[addLiteratureReference]
(hasEvent)	[Pathway:R-GGA-373920] Pyruvate metabolism
(precedingEvent)	[Reaction:R-GGA-373006] acetyl-CoA + H2O + oxaloacetate => citrate + CoA

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