Reactome | acetyl-CoA + H2O + oxaloacetate => citrate + CoA

Schema > Reaction > Entries

acetyl-CoA + H2O + oxaloacetate => citrate + CoA Show undefined attributes

authored	[InstanceEdit:376875] D'Eustachio, P, 2008-09-10 19:15:11
catalystActivity	[CatalystActivity:373008] citrate (Si)-synthase activity of citrate synthase dimer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:373012] D'Eustachio, P, 2008-07-11 14:25:46
dbId	373006
displayName	acetyl-CoA + H2O + oxaloacetate => citrate + CoA
edited	[InstanceEdit:376875] D'Eustachio, P, 2008-09-10 19:15:11
eventOf	[Pathway:R-GGA-372987] The tricarboxylic acid cycle - Gallus gallus
followingEvent	[Reaction:R-GGA-373015] citrate <=> isocitrate - Gallus gallus
input	[SimpleEntity:R-ALL-113559] Ac-CoA [mitochondrial matrix] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-113587] OA [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:373004] Crystal structure of an open conformation of citrate synthase from chicken heart at 2.8-A resolution
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	acetyl-CoA + H2O + oxaloacetate => citrate + CoA
output	[SimpleEntity:R-ALL-29654] CIT [mitochondrial matrix] [SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix]
precedingEvent	[Reaction:R-GGA-373177] pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ - Gallus gallus [Reaction:R-GGA-373047] malate + NAD+ <=> oxaloacetate + NADH + H+ - Gallus gallus
releaseDate	2009-06-01
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-373006
summation	[Summation:373011] Mitochondrial citrate synthase catalyzes the reaction of ace...

Referrals

(hasEvent)	[Pathway:R-GGA-372987] The tricarboxylic acid cycle
(precedingEvent)	[Reaction:R-GGA-373015] citrate <=> isocitrate

Cite Us!