Reactome | isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+

Schema > Reaction > Entries

isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ Show undefined attributes

authored	[InstanceEdit:376875] D'Eustachio, P, 2008-09-10 19:15:11
catalystActivity	[CatalystActivity:373023] isocitrate dehydrogenase (NAD+) activity of IDH3-like [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:373028] D'Eustachio, P, 2008-07-11 14:25:57
dbId	373024
displayName	isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+
edited	[InstanceEdit:376875] D'Eustachio, P, 2008-09-10 19:15:11
eventOf	[Pathway:R-GGA-372987] The tricarboxylic acid cycle - Gallus gallus
followingEvent	[Reaction:R-GGA-373042] 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ - Gallus gallus
inferredFrom	[Reaction:R-HSA-70967] IDH3 complex decarboxylates isocitrate - Homo sapiens
input	[SimpleEntity:R-ALL-29938] ISCIT [mitochondrial matrix] [SimpleEntity:R-ALL-113526] NAD+ [mitochondrial matrix]
isInDisease	false
isInferred	true
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+
output	[SimpleEntity:R-ALL-113594] 2OG [mitochondrial matrix] [SimpleEntity:R-ALL-29376] CO2 [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-29362] NADH [mitochondrial matrix]
precedingEvent	[Reaction:R-GGA-373015] citrate <=> isocitrate - Gallus gallus
releaseDate	2009-06-01
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-373024
summation	[Summation:373027] Mitochondrial isocitrate dehydrogenase (IDH3-like) catalyzes...

Referrals

(hasEvent)	[Pathway:R-GGA-372987] The tricarboxylic acid cycle
(precedingEvent)	[Reaction:R-GGA-373042] 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+
(inferredTo)	[Reaction:R-HSA-70967] IDH3 complex decarboxylates isocitrate

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