Reactome | Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2

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Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 Show undefined attributes

category	transition
compartment	[Compartment:1598585] chromosome [Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10782134
displayName	Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2
eventOf	[Pathway:R-GGA-2470946] Cohesin Loading onto Chromatin - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-2468039] Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 - Gallus gallus
inferredFrom	[Reaction:R-HSA-2470935] Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 - Homo sapiens
input	[DefinedSet:R-ALL-2537690] Chromatin [chromosome] 2 × [Complex:R-GGA-2468042] Cohesin:PDS5:WAPAL [nucleoplasm] 2 × [Complex:R-GGA-2470930] NIPBL:MAU2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2
output	[DefinedSet:R-GGA-2537688] Cohesin:PDS5:WAPAL:NIPBL:MAU2:Chromatin [nucleoplasm]
precedingEvent	[Reaction:R-GGA-2468040] Cohesin binds PDS5 and WAPAL - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2470935
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-2470946] Cohesin Loading onto Chromatin
(precedingEvent)	[Reaction:R-GGA-2468039] Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2
(inferredTo)	[Reaction:R-HSA-2470935] Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2

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