Reactome | Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2

Schema > Reaction > Entries

Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 Show undefined attributes

catalystActivity	[CatalystActivity:10782091] N-acetyltransferase activity of ESCO [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm [Compartment:1598585] chromosome
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10782093
displayName	Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2
eventOf	[Pathway:R-GGA-2468052] Establishment of Sister Chromatid Cohesion - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2468039] Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113560] Ac-CoA [nucleoplasm] [Complex:R-GGA-2545179] Cohesin:PDS5:WAPAL:Chromosomal Arm [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2
output	[Complex:R-GGA-2473153] Ac-Cohesin:PDS5:WAPAL:Chromosomal Arm [nucleoplasm] 2 × [SimpleEntity:R-ALL-2485002] CoA-SH [nucleoplasm]
precedingEvent	[Reaction:R-GGA-2470935] Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2468039
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-2468052] Establishment of Sister Chromatid Cohesion
(inferredTo)	[Reaction:R-HSA-2468039] Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2

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