Reactome | Biosynthesis of Lipoxins (LX)

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Biosynthesis of Lipoxins (LX) Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10826543
displayName	Biosynthesis of Lipoxins (LX)
eventOf	[Pathway:R-GGA-9018678] Biosynthesis of specialized proresolving mediators (SPMs) - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2267200] lipoxin biosynthetic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-GGA-266051] 5S-HpETE is dehydrated to LTA4 by ALOX5 - Gallus gallus [Reaction:R-GGA-2161917] ALOX5 oxidises 15S-HpETE to LXA4/B4 - Gallus gallus [Reaction:R-GGA-2161907] ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 - Gallus gallus [Reaction:R-GGA-2161779] LXA4 is oxidised to 15k-LXA4 by HPGD - Gallus gallus
inferredFrom	[Pathway:R-HSA-2142700] Biosynthesis of Lipoxins (LX) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Biosynthesis of Lipoxins (LX)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-2142700
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9018678] Biosynthesis of specialized proresolving mediators (SPMs)
(inferredTo)	[Pathway:R-HSA-2142700] Biosynthesis of Lipoxins (LX)

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