Reactome | PRC2 recruits DNA methyltransferases

Schema > Reaction > Entries

PRC2 recruits DNA methyltransferases Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10750883
displayName	PRC2 recruits DNA methyltransferases
eventOf	[Pathway:R-GGA-212300] PRC2 methylates histones and DNA - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-GGA-212269] DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 - Gallus gallus
inferredFrom	[Reaction:R-HSA-212222] PRC2 recruits DNA methyltransferases - Homo sapiens
input	[DefinedSet:R-GGA-212315] DNMT1,3A,3B [nucleoplasm] [Complex:R-GGA-5084071] PRC2 Core:Chromatin [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PRC2 recruits DNA methyltransferases
output	[Complex:R-GGA-212288] DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-GGA-212252] Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-212222
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-212300] PRC2 methylates histones and DNA
(precedingEvent)	[BlackBoxEvent:R-GGA-212269] DNMT1,3A,3B:PRC2 methylates cytosine and histone H3
(inferredTo)	[Reaction:R-HSA-212222] PRC2 recruits DNA methyltransferases

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