Reactome | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

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APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10826031
displayName	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
eventOf	[Pathway:R-GGA-174143] APC/C-mediated degradation of cell cycle proteins - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:161960] anaphase-promoting complex-dependent catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-174088] Association of cell cycle proteins with the APC/C:Cdh1 complex - Gallus gallus [Reaction:R-GGA-174195] Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex - Gallus gallus [BlackBoxEvent:R-GGA-174105] Degradation of multiubiquitinated cell cycle proteins - Gallus gallus [Reaction:R-GGA-9686980] RB1 recruits APC/C:Cdh1 complex to SKP2 - Gallus gallus [Reaction:R-GGA-9686969] APC/C:Cdh1 polyubiquitinates SKP2 - Gallus gallus [BlackBoxEvent:R-GGA-188191] APC/C:Cdh1-mediated degradation of Skp2 - Gallus gallus
inferredFrom	[Pathway:R-HSA-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-174178
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-174143] APC/C-mediated degradation of cell cycle proteins
(inferredTo)	[Pathway:R-HSA-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

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