Reactome | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

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APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Show undefined attributes

authored	[InstanceEdit:174241] Lorca, T, Castro, A, 2006-01-26 00:00:00
created	[InstanceEdit:174149] Matthews, L, 2006-02-17 00:41:48
crossReference	[DatabaseIdentifier:12325458] BioModels Database:BIOMD0000000186 [DatabaseIdentifier:12325414] BioModels Database:BIOMD0000000293 [DatabaseIdentifier:12325416] BioModels Database:BIOMD0000000220 [DatabaseIdentifier:12325460] BioModels Database:BIOMD0000000187 [DatabaseIdentifier:12325570] BioModels Database:BIOMD0000000954
dbId	174178
displayName	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
edited	[InstanceEdit:174183] Matthews, L, 2006-01-30 00:00:00
eventOf	[Pathway:R-HSA-174143] APC/C-mediated degradation of cell cycle proteins - Homo sapiens
figure	[Figure:177044] /figures/Cdh1.targets.jpg
goBiologicalProcess	[GO_BiologicalProcess:161960] anaphase-promoting complex-dependent catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-174088] Association of cell cycle proteins with the APC/C:Cdh1 complex - Homo sapiens [Reaction:R-HSA-174195] Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex - Homo sapiens [BlackBoxEvent:R-HSA-174105] Degradation of multiubiquitinated cell cycle proteins - Homo sapiens [Reaction:R-HSA-9686980] RB1 recruits APC/C:Cdh1 complex to SKP2 - Homo sapiens [Reaction:R-HSA-9686969] APC/C:Cdh1 polyubiquitinates SKP2 - Homo sapiens [BlackBoxEvent:R-HSA-188191] APC/C:Cdh1-mediated degradation of Skp2 - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:174118] The anaphase-promoting complex: a key factor in the regulation of cell cycle [LiteratureReference:176915] The processivity of multiubiquitination by the APC determines the order of substrate degradation
modified	[InstanceEdit:12325341] Wright, Adam, 2024-02-14
name	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
orthologousEvent	[Pathway:R-DDI-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Dictyostelium discoideum [Pathway:R-DME-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Drosophila melanogaster [Pathway:R-GGA-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Gallus gallus [Pathway:R-XTR-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Xenopus tropicalis [Pathway:R-SSC-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Sus scrofa [Pathway:R-BTA-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Bos taurus [Pathway:R-CFA-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Canis familiaris [Pathway:R-RNO-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Rattus norvegicus [Pathway:R-MMU-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Mus musculus
releaseDate	2006-04-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:177300] Peters, JM, 2006-03-27 22:55:09
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-174178
summation	[Summation:176416] From late mitosis through G1 phase APC/C:Cdh1 insures the c...

Referrals

(hasEvent)

[Pathway:R-HSA-174143] APC/C-mediated degradation of cell cycle proteins