Reactome | Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex

Schema > Reaction > Entries

Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex Show undefined attributes

catalystActivity	[CatalystActivity:10743571] ubiquitin-protein transferase activity of cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10743573
displayName	Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex
eventOf	[Pathway:R-GGA-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-GGA-174105] Degradation of multiubiquitinated cell cycle proteins - Gallus gallus [Reaction:R-GGA-174057] Multiubiquitination of APC/C-associated Cdh1 - Gallus gallus
goBiologicalProcess	[GO_BiologicalProcess:7441] ubiquitin-dependent protein catabolic process
inferredFrom	[Reaction:R-HSA-174195] Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex - Homo sapiens
input	[Complex:R-GGA-174107] cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] 4 × [DefinedSet:R-GGA-113595] Ub [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex
output	[Complex:R-GGA-174248] multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol]
precedingEvent	[Reaction:R-GGA-174088] Association of cell cycle proteins with the APC/C:Cdh1 complex - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-174195
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
(precedingEvent)	[BlackBoxEvent:R-GGA-174105] Degradation of multiubiquitinated cell cycle proteins [Reaction:R-GGA-174057] Multiubiquitination of APC/C-associated Cdh1
(inferredTo)	[Reaction:R-HSA-174195] Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex

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