Reactome | Recycling of bile acids and salts

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Recycling of bile acids and salts Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10825805
displayName	Recycling of bile acids and salts
eventOf	[Pathway:R-GGA-194068] Bile acid and bile salt metabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:24849] bile acid and bile salt transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-5340195] NR1H4 binds DCA, CDCA, LCHA - Gallus gallus [Reaction:R-GGA-5340251] NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 - Gallus gallus [Reaction:R-GGA-194187] SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol - Gallus gallus [BlackBoxEvent:R-GGA-9733973] Bile salts bind FABP6 - Gallus gallus [BlackBoxEvent:R-GGA-9733969] Bile salts dissociate from FABP6 - Gallus gallus [Reaction:R-GGA-194153] ABCC3 transports bile salts from cytosol to extracellular region - Gallus gallus [Reaction:R-GGA-9733964] SLC51A:SLC51B transports bile salts from cytosol to extracellular region - Gallus gallus [BlackBoxEvent:R-GGA-9733545] Bile salts and acids bind ALB - Gallus gallus [BlackBoxEvent:R-GGA-9733960] Bile salts and acids dissociate from ALB - Gallus gallus [Reaction:R-GGA-194121] SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol - Gallus gallus [Reaction:R-GGA-194130] Transport (influx) of bile salts and acids by OATP-A - Gallus gallus [Reaction:R-GGA-194083] SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol - Gallus gallus [Reaction:R-GGA-194079] SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol - Gallus gallus [Reaction:R-GGA-8873850] STARD5 binds DCA, LCA - Gallus gallus [Reaction:R-GGA-159425] Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) - Gallus gallus [Reaction:R-GGA-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine - Gallus gallus [Reaction:R-GGA-193362] ABCB11 transports bile salts from cytosol to extracellular region - Gallus gallus
inferredFrom	[Pathway:R-HSA-159418] Recycling of bile acids and salts - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Recycling of bile acids and salts
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-159418
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-194068] Bile acid and bile salt metabolism
(inferredTo)	[Pathway:R-HSA-159418] Recycling of bile acids and salts

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