Reactome | SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol

Schema > Reaction > Entries

SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10746374] bile acid:sodium symporter activity of SLC10A1 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10746376
displayName	SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol
eventOf	[Pathway:R-GGA-159418] Recycling of bile acids and salts - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-193362] ABCB11 transports bile salts from cytosol to extracellular region - Gallus gallus
inferredFrom	[Reaction:R-HSA-194121] SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol - Homo sapiens
input	[DefinedSet:R-ALL-192483] bile salts and acids [extracellular region] 2 × [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol NTCP takes up bile salts and Na+ into the liver
output	[DefinedSet:R-ALL-194156] bile salts and acids [cytosol] 2 × [SimpleEntity:R-ALL-83910] Na+ [cytosol]
precedingEvent	[Reaction:R-GGA-194153] ABCC3 transports bile salts from cytosol to extracellular region - Gallus gallus [BlackBoxEvent:R-GGA-9733545] Bile salts and acids bind ALB - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-194121
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-159418] Recycling of bile acids and salts
(precedingEvent)	[Reaction:R-GGA-193362] ABCB11 transports bile salts from cytosol to extracellular region
(inferredTo)	[Reaction:R-HSA-194121] SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol

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