Reactome | Hemoglobin A is protonated and carbamated causing release of oxygen

Schema > Reaction > Entries

Hemoglobin A is protonated and carbamated causing release of oxygen Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10770099
displayName	Hemoglobin A is protonated and carbamated causing release of oxygen
eventOf	[Pathway:R-GGA-1237044] Erythrocytes take up carbon dioxide and release oxygen - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1237325] Hemoglobin A is protonated and carbamated causing release of oxygen - Homo sapiens
input	4 × [SimpleEntity:R-ALL-113528] CO2 [cytosol] 4 × [SimpleEntity:R-ALL-70106] H+ [cytosol] [Complex:R-GGA-1237320] OxyHbA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Hemoglobin A is protonated and carbamated causing release of oxygen Bohr Effect
output	4 × [SimpleEntity:R-ALL-29368] O2 [cytosol] [Complex:R-GGA-1237312] Protonated Carbamino DeoxyHbA [cytosol]
precedingEvent	[Reaction:R-GGA-1237069] RHAG transports CO2 from extracellular region to cytosol - Gallus gallus [Reaction:R-GGA-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-1237325
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-1237044] Erythrocytes take up carbon dioxide and release oxygen
(inferredTo)	[Reaction:R-HSA-1237325] Hemoglobin A is protonated and carbamated causing release of oxygen

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