Reactome | DENV circular genomic +ssRNA:RC [endoplasmic reticulum membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9922962] RNA-directed RNA polymerase activity of DENV circular genomic +ssRNA:RC [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane
consumedByEvent	[BlackBoxEvent:R-HSA-9922955] NS5 synthesizes minus strand genome - Homo sapiens
created	[InstanceEdit:9979975] Stephan, Ralf, 2026-01-23
dbId	9979976
deleted	[Deleted:9979980] Deletion of instance: 9922954
displayName	DENV circular genomic +ssRNA:RC [endoplasmic reticulum membrane]
hasComponent	[EntityWithAccessionedSequence:R-DVI-9922609] DENV m7G(5')pppAm-capped genomic +ssRNA [cytosol] [Complex:R-DVI-9979859] Replication complex (RC) [endoplasmic reticulum membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	5
modified	[InstanceEdit:9980057] Stephan, Ralf, 2026-01-24
name	DENV circular genomic +ssRNA:RC
negativelyRegulates	[NegativeRegulation:9947760] Negative regulation by 'DENV circular genomic +ssRNA:RC [endoplasmic reticulum membrane]'
producedByEvent	[BlackBoxEvent:R-HSA-9922965] Circularization of (+)-genomic RNA - Homo sapiens
schemaClass	Complex
species	[Species:3244621] Dengue virus type 2
stId	R-DVI-9979976

(replacementInstances)	[Deleted:9979980] Deletion of instance: 9922954
(output)	[BlackBoxEvent:R-HSA-9922965] Circularization of (+)-genomic RNA
(input)	[BlackBoxEvent:R-HSA-9922955] NS5 synthesizes minus strand genome
(physicalEntity)	[CatalystActivity:9922962] RNA-directed RNA polymerase activity of DENV circular genomic +ssRNA:RC [endoplasmic reticulum membrane]
(regulator)	[NegativeRegulation:9947760] Negative regulation by 'DENV circular genomic +ssRNA:RC [endoplasmic reticulum membrane]'

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